Comparative sensitivities of ThinPrep and Papanicolaou smear for adenocarcinoma in situ (AIS) and combined AIS/high-grade squamous intraepithelial lesion (HSIL): Comparison with HSIL

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Nov2005: Letters to the Editors

I read with interest the article by Ozkan and colleagues1 on glandular lesions of the cervix on thinlayer Pap tests. However, a few clarifications need to be made. The authors commented on the difficulty distinguishing endocervical adenocarcinoma in situ (AIS) from high grade squamous intraepithelial lesion (HSIL) involving endocervical glands. Of the 37 ThinPrep® Pap TestsTM (Cytyc Corporation...

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Pathogenesis of combined high-grade squamous intraepithelial lesion and adenocarcinoma in situ of the uterine cervix: human papillomavirus genotype and methylation status and immunohistochemical study.

To determine the etiology of combined high-grade squamous intraepithelial lesion (HSIL) and adenocarcinoma in situ (AIS) of the uterine cervix, we examined human papillomavirus (HPV) subtypes, methylation status of the HPV-16 L1 gene, and immunohistochemical staining pattern of Krt7 in 8 cases of combined HSIL and AIS. Overall, 6 (75%) of 8 patients with combined HSIL and AIS were infected by t...

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Evaluation of CellSolutions BestPrep® automated thin-layer liquid-based cytology Papanicolaou slide preparation and BestCyte® cell sorter imaging system.

OBJECTIVE A double-blind study was conducted to compare the performance of the new BestPrep® (CellSolutions) liquid-based thin-layer Papanicolaou (Pap) test with ThinPrep® (Hologic). STUDY DESIGN Samples from the study patients (n = 105) were collected twice in the same encounter with the ThinPrep sample always taken first and the BestPrep sample collected second. Slides were prepared accordi...

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Assessment of p16 and Ki67 Immunohistochemistry Expression in Squamous Intraepithelial Lesion with Cytohistomorphological Correlation

Background & Objective: Cervical cancer is the most common cancer in women worldwide with high mortality, necessitating quicker diagnostic methods. We wish to enhance th...

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a comparison of teachers and supervisors, with respect to teacher efficacy and reflection

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ژورنال

عنوان ژورنال: Cancer

سال: 2007

ISSN: 0008-543X

DOI: 10.1002/cncr.23117